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Insulin Resistance and Pregnancy

 
There is some research to suggest an association between Insulin Resistance and two common conditions of pregnancy, gestational diabetes and pregnancy induced hypertension. These are still developing associations, but it makes sense, as Insulin Resistance affects insulin use in the body, blood sugar as well as the cardiovascular system, seen in syndrome X and Insulin Resistance Syndrome..
Keep on the alert for more articles along this line. Here are some of the current abstracts of research for t his area.
Gestational Diabetes
Pregnancy Induced Hypertension
http://www.fpnotebook.com/CV155.htm
http://www.fpnotebook.com/CV156.htm
Prevention: http://www.fpnotebook.com/CV159.htm
MMT: http://www.fpnotebook.com/CV157.htm
 
Mechanism for Insulin Resistance in Pregnancy
 
Insulin resistance and its potential role in pregnancy-induced hypertension.
J Clin Endocrinol Metab. 2003 Jun;88(6):2393-8.
Insulin Resistance Syndrome
http://www.wdxcyber.com/ngen10.htm
Many women with polycystic ovaries have this as well as women who have gestational diabetes in pregnancy. Up to 50% of patients with hypertension are estimated to have insulin resistance. The main problem is that this condition can exist unrecognized and metabolic damage can occur before a full blown Type 2 diabetes is finally diagnosed. Insulin resistant diabetics are 2-5 times more likely to die from heart attack or stroke than are non diabetics.
 
Impact of Insulin Resistance on Pregnancy Complications and Outcome in Women with Polycystic Ovary Syndrome
 
INSULIN RESISTANCE AND HYPERINSULINEMIA
 
TNF-{alpha} Is a Predictor of Insulin Resistance in Human Pregnancy
http://diabetes.diabetesjournals.org/cgi/reprint/51/7/2207.pdf

Pat Sonnenstuhl, RN, CNM, Nutrition Support

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Disclaimer: The focus of this site is non-pharmaceutical management, but rather the basics of prevention. Please check with your health care provider about specific pharmaceutical management.

If you suspect you have IR or one if its associated conditions, please seek accurate diagnosis and research thoroughly all aspects of the conditions. I recommend working carefully with your health care provider, to learn what is the most appropriate management for you.

Updated 5-2-2008