Inversion 10 Karyotype



chromosome 10 inversion karyotype


This karyotype is an example of an inversion, one of the more common structural rearrangements. In this case a segment in the q, or long arm of the right chromosome 10 is inverted. Since both breaks occurred in the long arm and the centromere is not involved, this is referred to as a paracentric inversion. If separate breaks had occurred in both the long and short arms the centromere would be inverted as well, this would be called a pericentric inversion. The karyotype is written as: 46,XY,inv(10)(q11.23q26.3). The key to the karyotype description is as follows:
  • 46:  the total number of chromosomes.

  • XY:  the sex chromosomes (male).

  • inv(10):  inversion in chromosome 10.

  • (q11.23q26.3):  breakpoints of the inverted segment.


The following ideogram gives a detailed illustration of this inversion. To view an animation of this process click here .

inversion 10 ideogram



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