Newborn female, dysmorphic facial features
CT 3D reconstructions (anterior view)
Diffuse thinning of cortical mantle with absence of septum. Fused thalami and orbits.
For cortical thinning: Severe hydrocephalus, hydranencephaly, holoprosencephaly.
Absence of septum help distinguish holoprosencephaly from the other DDx.
Submitted by Paritosh Khanna, MD, UW Neuroradiology FellowReturn to UW Neuroradiology Teaching Files