22 month old with microphthalmia




               
T1 axial                                                                                                                                                     T2 axial                                                                                       




Findings:

Bilateral thickened gryi particularly in the frontal lobes

DDX:

pachygyria, lissencephaly, polymicrogyria



Diagnosis:

Symmetric Pachygyria


Discussion:

The term 'pachygyria' is not specific to a particular malformation but describes the gross  physical appearance of the brain in association with several neuronal migration disorders - most commonly disorders relating to varied degrees of lissencephaly.



Submitted by Kevin Stevenson, MD, UW Neuroradiology Fellow

Return to UW Neuroradiology Teaching Files