Abstract

Introduction

The danger of non-lytic viruses

T cells kill virally-silenced bystanders

Do T cells discover aberration with FasL?

Danger receptors on T cells

A self-referential danger model

Why reference targets should be syngeneic

Superantigens and killer T cells

Dendritic cells and early viral proteins

Peripheral tolerance

Implications for cancer immunotherapy

Reference cells and tumor tolerance

Virally based cancer immunotherapy

References

Forden's Immunology Home page

.PDF version of this paper, from Elsevier