THE GENETICS PAGE
Try
DNA from the Beginning
- (EXCELLENT SITE!!)
an animated and interactive site, with the basics of DNA, genes and heredity.
Human Genetics Powerpoint
Newborn Screening Information- Save Babies Through Screening
National Newborn Screening Status Report
I.
Class Information
A.
Genetics Problems-----
With Answers and Solutions!!
B.
Notes
-
exons/introns
(
diagram
)
;
genes (
diagram
)
mutations (
diagram
);
types
C.
Table Of The Genetic Code;
D.
Genetic code
E.
Barr bodies
F.
Chromosome FAQ's
G. Chromosomes-
diagram
;
photograph of human chromosomes
photograph of X and Y chromosomes
diagram of DNA packaging into chromosomes
H.
DNA fingerprinting
I.
Karyotypes;
Interactive Case Studies:
1
;
2
;
3
;
4
;
5
J. Pedigree-
general diagram
Hemophilia
and Royal Families of Europe
Interpreting pedigrees
K.
Polydactyly
-
human
L. Blue People of Kentucky:
Picture 1
;
Picture2
;
Picture3
The Blue People of Toublesome Creek
by Cathy Trost
, Science 82,
November 1982
Explanation;
Methemoglobinemia
Activity
II. Mendelian Genetics
A.
Gregor Mendel And His Principles
1. Mendelian Patterns of Inheritance-
U of Vermont
;
U of South Dakota
2.
Mendel's Experiment #1
- diagram
B.
Recessive and dominant inheritance
- diagram
C.
Dominant Disorders
- diagram
D.
Recessive Disorders
- diagram
E.
Sex-linked Disorders
- diagram
F.
Sex-linked inheritance:
Drosophila
- diagram
G.
Sex-linked inheritance: Hemophilia
- diagram
H
.
Problem sets and tutorials
- The Biology Project,
University of Arizona
I.
Two kinds of Disorders, two kinds of proteins
- explaining dominance/recessiveness
J.
MendelWeb
III. Genetic Engineering and Molecular Genetics
A.
PCR
B.
Gel electrophoresis
C.
Sequencing
D.
RFLP Analysis
E.
Microsatellites (simple sequence repeats)
F.
Marker Analysis
G. DNAi -
DNA Interactive
H.
Cloning into a plasmid
- diagram
I.
Transfer and cloning of the Insulin gene
- diagram
IV. Operons and Gene Control Mechanisms
A.
Repressor protein switching genes off and on
- diagram
B.
Control of the Human B-globin gene
- diagram
C.
Regulatory Protein Coordinating Gene Expression
- diagram
D.
Steps leading from Gene to Protein
- diagram
E.
Control of Gene Expression
- diagram
F.
Importance of Combinatorial Gene Control
- diagram
G.
Genes can be turned on and off
- part of the "DNA from the beginning" website
V. Biological Engineering
A.
Engineering cows to prevent Mad Cow disease
B.
Are bioengineered foods safe?
C.
Gene Therapy- an overview
D.
Biotechnology- the present and future
-
diagram
E.
Transgenic mice
- diagram
F.
Transgenic mice
- explained
G.
I Can Do That!- Genetic Engineering
-
A cartoon website devoted to DNA basics
V.
Human Genetics
A.
Find which genes are on each human chromosome
B.
Human Chromosome Map- Find which human diseases are on each chromosome
C.
The Meaning of Sex, Genes and Gender
Click the above link to try the following interactive sites:
Gender Testing of Female Athletes
Evolution of the Y Chromosome
Genomics Webcast: Eric Lander
D.
Human Genome Project Information
-
sponsored by US Dept of Energy
E.
Genes and Disease
-
a US NIH site
F. Cystic Fibrosis-
Stalking a lethal gene
G. Huntington's Disease-
In search of large families
H.
How to conquer a genetic disease
I.
Cancer as a genetic disease
VI. New Definitions:
A. YACs- Yeast artificial chromosomes
B. BACs- Bacteria artificial chromosomes
C. PACS- fragments of DNA in a vector derived from a bacteriophage known as P1
D. MACs- Mammalian artificial chromosomes
Miscellaneous Links
A.
The Beauty Of Mutations
- Why So Many Errors in Our DNA?
B.
Crossing Over: Genetic Recombination
C.
One Gene/One Enzyme Hypothesis-
Beadle and Tatum
D.
Transformation
E.
Bacterial Mutations-
Luria and Delbruck
F.
Birds Do It, Bees Do It
-
Lederberg and Tatum
G.
From Corned Beef To Cloning-
Cohen and Boyer
H.
Barbara McClintock
I.
Find chromosome numbers of different species
VI.
Some Genetic Traits of
Drosophila
- the fruit fly:
Return to Mrs. Pellegrini's Biology Page