When converting from valproic acid or Depakote® to
Depakote ER
®,
A.
Daily dosage should be increased by 8-20%
B.
Daily dosage should be decreased by 8-20%
C.
A 24-hour 'drug holiday' should be exercised before initiating Depakote ER® therapy
D.
The patient should be re-assessed for renal toxicity
E.
No dose adjustment is required.
(Click the correct answer)