• shortness of breath or trouble breathing
• slurred speech
• chest pain
• swelling of the face or throat
• weakness in one part or side of your body

Stop your NSAID medicine and call your healthcare provider right away if you have any of the following symptoms:

• Nausea
• Vomit blood
• There is blood in your bowel movement or it is black and sticky like tar
• More tired or weaker than usual
• Itching
• Your skin or eyes look yellow
• Unusual weight gain
• Stomach pain
• Skin rash or blisters with fever
• Flu-like symptoms
• Swelling of the arms and legs, hands and feet

These are not all the side effects with NSAID medicines.  Talk to your healthcare provider or pharmacist for more information about NSAID medicines.

Other information about Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Aspirin is an NSAID medicine  but it does not increase the chance of a heart attack. Aspirin can cause bleeding in the brain, stomach, and intestines. Aspirin can also cause ulcers in the stomach and intestines.

Some of these NSAID medicines are sold in lower doses without a prescription (over-the-counter). Talk to your healthcare provider before using over the counter NSAIDs for more than 10 days.

NSAID medicines that need a prescription

Also, be sure to read Pfizers offer to provide help and assistence if you are financially unable to pay for medication

NSAID medicines may increase the chance of a heart attack or stroke that can lead to death. This chance increases:
•  with longer use of NSAID medicines
•  in people who have heart disease.

NSAID medicines should never be used right before or after a heart surgery called a "coronary artery bypass graft (CABG)."
NSAID medicines can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding:
•  can happen without warning symptoms
• . may cause death

The chance of a person getting an ulcer or bleeding increases with: taking medicines called "corticosteroids" and "anticoagulants"

• longer use
• smoking
• drinking alcohol
• older age
• having poor health

NSAID medicines should only be used:

• exactly as prescribed
• at the lowest dose possible for your treatment
• for the shortest time needed

What are Non-Steroidal Anti-Inflammatory Drugs (NSAlDs)?

NSAID medicines are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as:
• different types of arthritis
• menstrual cramps and other types of short-term pain

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)?

Do not take an NSAID medicine:
• if you had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine
• for pain right before or after heart bypass surgery

Tell your healthcare provider:

• about all of your medical conditions. • about all of the medicines you take. NSAIDs and some other medicines can interact with each other and cause serious side effects.

Keep a list of your medicines to show to your healthcare provider and pharmacist.
• if you are pregnant. NSAID medicines should not be used by pregnant women late in their pregnancy.
• if you are breastfeeding. Talk to your doctor.

What are the possible side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAlDs)?

Serious side effects include:

• heart attack
• stroke
• high blood pressure
• heart failure from body swelling (fluid retention)
• kidney problems including kidney failure
• bleeding and ulcers in the stomach and intestine
• low red blood cells (anemia)
• life-threatening skin reactions
• life-threatening allergic reactions
• liver problems including liver failure
• asthma attacks in people who have asthma

Other side effects include:?

• stomach pain
• constipation
• diarrhea
• gas
• heartburn
• nausea
• vomiting
• dizziness

Get emergency help right away if you have any of the following symptoms:

• shortness of breath or trouble breathing
• slurred speech
• swelling of the face or throat
• chest pain
• weakness in one part or side of your body

Stop your NSAID medicine and call your healthcare provider right away if you have any of the following symptoms:

• nausea • there is blood in your bowel movement or it is black and sticky • more tired or weaker than usual • itching like tar • your skin or eyes look yellow • skin rash or blisters with fever • stomach pain • unusual weight gain • flu-like symptoms • swelling of the arms and legs,hands & feet • vomit blood

These are not all the side effects with NSAID medicines. Talk to your healthcare provider or pharmacist for more information about NSAID medicines.

When it comes to relieving arthritis pain, you may think some prescription NSAID pain relievers, like ibuprofen and naproxen, don't have any Cardiovascular risks.
But based on the available research, that's not clear.  And if you look closer,  the FDA requires all these NSAID pain relievers, including Celebrex, to have the same cardiovascular warning

What about heart attack or stroke?

Any prescription NSAID, including Celebrex, may increase the chance of heart attack or stroke, which can lead to death.
This chance increases if you have heart disease or risk factors for it, such as high blood pressure, or when NSAIDs are taken for long periods.

How do NSAIDs affect my stomach?

All NSAIDs, including Celebrex, also increase the chance of stomach and intestine problems, such as bleeding and ulcers, which can occur without warning and may cause death.
With any of these medicines, patients also taking aspirin and the elderly are at increased risk for stomach bleeding and ulcers.

What does this mean for Celebrex?

While all NSAIDs have some of the same warnings, they all treat arthritis pain. But since individual results may vary, having options is important.
An NSAID, like Celebrex, may be one option. In fact, prescription Celebrex has never been taken off the market. Based on the available data, the FDA stated that for certain patients Celebrex's benefits outweigh the risks. But only you and your doctor can make that decision.

What are the benefits?

In clinical studies, a lower percentage of patients on Celebrex reported indigestion, abdominal pain and nausea versus prescription ibuprofen and naproxen. Celebrex can be used with low-dose aspirin. Other prescription NSAIDs aren't generally recommended with aspirin.

What does it do for arthritis pain?

Celebrex relieves arthritis pain, stiffness and inflammation. Just one 200 mg. dose provides 24-hour relief.

Any other precautions?

Use at the lowest dose possible for the shortest time based on treatment goals.
Do not take Celebrex if you're pregnant or have had allergic reactions to aspirin or sulfonamides.
All NSAIDs, including Celebrex, increase the chance of serious skin reactions. And tell your doctor if you've had kidney or liver problemsp What next?

For many with arthritis pain, not treating is not an option. Talk to your doctor about Celebrex and see what's right for you. Visit www.celebrex.com or call 1-888-celebrex. But most importantly, your doctor can tell you about the risks and benefits of all NSAID pain relievers.

Talk to your doctor to...Understand the risk

Uninsured? Need help paying for medication? Pfizer has programs that can help., no matter your age or income.
You may even qualify for free Pfizer medicines.
Call 1-866-706-2400. Or visit  pfizerhelpfulanswers.com"
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