Seanol - Powerful
Antioxidant from the Sea is extreme at improving health (A must read)
is extreme at improving health (A must read)
By Dr. Robert J. Rowen on 11/25/2008
Iíve brought you some powerful healing information in the past years. But this takes the cake. It even blew me away when I first learned about it. You see, researchers have discovered a new antioxidant thatís many times more powerful than anything else you may be taking.
This new wonder from the sea could transform almost all of your health problems. It has the power to reverse heart disease and osteoporosis. And there are many studies on its effectiveness for everything from fibromyalgia to diabetes, dementia, and much, much more.
You may remember some of the evidence Iíve shown you through the years of the effectiveness of flavonoids. Flavonoids are a well-known class of plant-made chemicals that act as antioxidants. We also call them polyphenols.
You already know how important antioxidants are to your health. The power of an antioxidant rests in its structure, which is made up of rings. Nature puts rings together for many different purposes. Polyphenols use the rings to capture stray electrons from free radicals.
So the more rings a polyphenol has, the better it works.
Most flavonoids have three interconnected rings. Catechins from green tea have four. But the ring structure of all these pales in comparison to this newly discovered polyphenol called Seanol. And it has up to eight interconnected rings.
That makes the Seanol molecule a veritable electron (i.e., free radical) trapping machine! These molecules beat the free-radical scavenging ability of most polyphenols by 10-100 times. That means they far outshine even the extremely powerful green tea catechins. The name ďSeanolĒ comes from the source of the compounds ó the sea. We find these compounds in several red and brown algae, in particular cava Ecklonia. This seaweed grows at a depth of about 100 feet.
This fact gives Seanol another major difference from the other polyphenols. Virtually all polyphenols from land sources are water-soluble. Water-soluble polyphenols have a short half-life in your body. Water-soluble compounds also have less ability to penetrate your blood brain barrier. Seanol compounds are 40% fat-soluble. This means they have a greater ability to get into your brain and protect it.
Like fat-soluble vitamins (such as vitamins A and D), it also means a much longer half-life in your body. The half-life of Seanol compounds is up to 12 hours compared to 30 minutes for water-soluble polyphenols.
Dr. Haengwoo Lee, a Korean biochemist now living near Seattle, Washington, found this difference makes Seanol much more effective in its treatment ability. He and his team of PhDs and MDs have researched the properties of Seanol compounds for the past 14 years. And they have the resources, with more than $30 million of public and private funding, to do highly credible work. Their research has included test-tube experiments, animal models, and now more than seven human trials. Iím amazed at the stunning results his team of scientists has found.
First, consider safety. The team hasnít found any toxicity at any level. In a fibromyalgia study, there were some cases of diarrhea. But the patients already had a pre-existing tendency for the same. However, the Seanol supplement they used also contained magnesium, which can stimulate diarrhea. Researchers in Korea conducted the animal studies needed to register Seanol as a safe food substance with their FDA. They found no toxicity.
Now that you understand how Seanol works and how safe it is, letís look at how it effectively works on so many health problems.
Starting with your heart, Seanol can work wonders with vascular disease or hypertension. One of the big causes of both of these could be thick blood. Thereís a special protein in your blood that dissolves unwanted clots. We call it plasmin. Unfortunately, many people have inhibitors (called antiplasmin) of this protein. That could be due to genetics, excess weight, toxins, diet, and more. Seanol compounds block antiplasmin. That can fix a tendency toward clots and thick blood!
PT is a common measure of thickness of your blood. A higher PT means thinner blood. If youíre taking coumadin (rat poison), your doctors will definitely be following your PT to make sure your blood is not too thin. But Seanol naturally thins your blood without danger of thinning it too much. One study on Seanol compounds found a small but significant rise in the PT and a fall in fibrinogen levels. Fibrinogen is the precursor protein to a clot. Generally, a lower fibrinogen level means less inflammation and a normal clotting system. Just this effect alone will have profound favorable effects on all circulatory and inflammatory diseases!
If you have hypertension, itís likely your doctor tried to put you on the popular ACE inhibitors. ACE inhibitors block a kidney enzyme system than can generate hypertension. Seanol compounds can potently suppress your ACE similar to the drug (enalapril) Vasotec, but better. When researchers gave rats the drug, they had rebound hypertension after stopping the drug. Seanol rats did not!
Inflamed blood vessels near your nerves will often cause nerve pain (neuropathy). Researchers recently studied Seanol on 40 patients with neuropathy. It reduced the nerve pain by a stunning 40% in just four weeks. And 80% of the patients responded favorably.
Seanol also helps improve coronary artery disease (CAD). As a reader of Second Opinion, you may know that coronary disease is not due to cholesterol, as the statin peddlers want you to believe. Damage done to your arterial walls is determined more by how your body handles cholesterol than by the cholesterol itself. You donít want your LDL cholesterol to oxidize. When it does, it will definitely damage your arteries.
Researchers discovered that Seanol is more potent at inhibiting the oxidation of LDL than green tea catechins! It can actually scrub the plaque off your endothelial lining. And it can reduce vascular inflammation.
So it stands to reason that Seanol would protect you from cholesterol and it lowers it, too. Look at these results: Researchers gave 39 adults (average age 55.6) 100 mg Seanol compounds for six weeks. Their average cholesterol dropped from 228 to 224. LDL dropped from 141 to 135. The hard-to-raise HDL rose from 46.5 to 50.7 (highly significant). Triglycerides fell from 215 to 195. And the atherogenic index (a key atherosclerosis score) dropped a whopping 12.5%. All this with no lifestyle changes! (And remember that Seanol blocks oxidation of the ďbadĒ LDL cholesterol.)
How can Seanol work so well? A human study showed that Seanol can regenerate your all-important vascular endothelium. These cells are the critical inner lining of your blood vessels. They generate the chemical nitric oxide (NO), which keeps the arterial wall relaxed and dilated. In one study, CAD patients were given Seanol for six weeks. Then the researchers measured blood flow controlled by NO. Flow increased 50-60%. This suggests Seanol can rejuvenate damaged endothelial cells to make NO.
Because Seanol improves blood flow so well, it makes sense that it would improve your memory. Eight million Americans are believed to have ďmildĒ cognitive decline. All the approved drugs are highly toxic. So itís vital for you to find powerful nutrients that can get into your brain and help it work more efficiently. Iíve already shown you how Seanol can cross over the blood-brain barrier. Now letís see how Seanol works once itís in there.
Memory is dependent on the neurotransmitter acetylcholine (ACh). Seanol increased rodent ACh by 140% in brain regions responsible for learning and memory.
And it did this after just seven days administration! Seanol compounds can easily neutralize the neurotoxic free-radical peroxynitrite. But its power is even more fantastic than that.
National Institutes of Health scientists at aging research labs in Baltimore studied Seanol in rats. They found it inhibits beta-amyloid deposition in their brains. Thatís the nasty stuff that accumulates in Alzheimerís brains. These rats also learned maze challenges faster. That shows improvement in short-term memory, so vulnerable in cognitive decline.
Your carotid arteries feed your brain. Dr. Leeís group found that Seanol can increase the velocity of blood flow in this important artery from an average of 36.68 cm/sec. to 40.09 cm/sec. The placebo showed no improvement. An EEG study on brain waves on healthy middle-age volunteers found that Seanol compounds increase alpha waves. Alpha waves are an indicator of relaxation. So this is a good indication that Seanol is relaxing the blood vessels and balancing your brainís activity.
And yet another study found that Seanol compounds prevented sleepiness in bus drivers and in high school students during daytime activities. Again, this is likely due to increased blood flow and oxygen delivery.
Obviously, Seanol is an incredible nutrient. My favorite brand of Seanol is FibroBoost. At my urging, it has now been added to the Advanced Bionutritionals product line. You can order it here.
But please keep reading. Youíll see that Seanol also can help with diabetes, weight loss, inflammation, and even fibromyalgia.
If youíre overweight, you already know how difficult it is to lose weight. The enzyme DGAT is a big reason why. It is the final step in the synthesis of triglycerides. You have probably seen triglyceride measurements as part of your cholesterol panels. Triglycerides are circulating fat bodies that ultimately wind up in your fat cells. They are almost always elevated in diabetes. They also have emerged as a major risk factor in vascular disease.
Dr. Haengwoo Lee, whom I mentioned earlier, found that Seanol compounds inhibit DGAT by more than 50%. Dr. Lee used Seanol to control DGAT in laboratory mice. His research shows that Seanol reduced their body fat and increased their physical activity. But, most importantly, it encouraged leanness in the animals and resistance to a high-fat diet. Obese mice lost more than 10% of their weight in just 120 days! They had shiny skin, no side effects, and were more alert.
In another study, 141 young adults were given a beverage containing Seanol at a daily dose of 200 mg daily. In just two weeks, their average weight dropped nearly two-and-a-half pounds, muscle mass increased by two-and-a-half pounds, and body fat dropped over four pounds. Body fat in this group dropped a stunning and highly statistically significant 7.48%. Seanol blocks fat creation and stimulates the body to burn it by increasing muscle mass.
We already know that dietary fat directly impairs your insulin metabolism. Fat blocks your pancreas from making insulin. A recent mouse study showed that Seanol reverses fat deposition in liver and pancreas cells. The yet unpublished data was produced by Dr. Lee at the University of Washington Pathology Department. His team fed Seanol to genetically engineered fat mice. It caused a 10% reduction in blood glucose and literally removed fat. Controls fed the same diet got 10% worse. Doesnít it make sense that a substance that reduces pancreas fat accumulation might restore insulin production and reverse type-2 diabetes? But the good news doesnít stop there.
How effective is Seanol at treating high blood sugar? My friend Ron MacDonald has had a long-term problem with diabetes. Ron had followed my strict dietary suggestions. He got a splint from Dr. Robson for his life-threatening sleep apnea. He took supplements. We managed to eliminate his two diabetic drugs, Glyburide and Metformin. We completely eliminated his craving for two pots of coffee down to a maximum of just one cup. But Ron continued with morning blood sugars in the range of 140 mg. (Of course, this was down considerably from the 300 level when we first met.)Within two weeks of starting Seanol, his blood sugar approach 100 mg. Furthermore, it rapidly normalized after he cheated and ate wedding cake. Before the Seanol, that indiscretion would have sent his glucose to over 300. It would take more than two days to normalize, even with the two drugs and diet adherence.
And hereís one final point about Seanolís ability to treat diabetes. You may know that high blood sugar leads to vascular complications. One way that happens is through an enzyme called aldose reductase. This enzyme is present in your eyes, nerves, and many other parts of your body. When your blood sugar gets too high, this enzyme converts some of the excess glucose into a sugar alcohol called sorbitol. Sorbitol can build up in these critical cells and damage them.
In fact, recent research found that animals deficient in this enzyme were protected from retinal complications of diabetes. Seanol compounds are potent inhibitors of this enzyme. So if you have metabolic syndrome, syndrome X, or diabetes, this is one supplement you want to have in your medicine cabinet.
Seanol also has the ability to treat fibromyalgia. As you may know, this is a tricky condition. I believe there are many factors in its development. So thereís no uniform therapy. Iíve had excellent results in tailoring treatment to the physiology of each individual patient. But if you donít have access to a doctor who can do this for you, you might consider Seanol.
Hereís why: Fibronol, which is a supplement used to treat fibromyalgia, is rich in Seanol. When studied, researchers gave it to 36 participants. Of those, 29 completed the eight-week study. And the results were startling.
Seanol cut the time it took the participants to fall asleep by 47 minutes. It increased total nighttime sleep by 1.6 hours. It improved soundness of sleep by 80%. It boosted their energy level by 71%. It gave them 2 1/4 more good days per week. It helped reduce their pain by 31%. And the general condition improved by 39%.
Amazingly, all this improvement came at all doses. Patients given the placebo had no improvement during their two weeks on it.
Now when you think about the improvement in sleep for fibromyalgia patients and the increased alertness for high school students and bus drivers, you might wonder what is going on. Are the results conflicting? Hardly. The product is stimulating ideal function. If you sleep better, youíll be more alert when you need to be.
The more than 50 million Americans with various sleep disorders might well benefit from Fibronol, without the fears of addiction from prescription sleep aids.
I donít know if Iíve ever seen one nutrient that could do more for you than Seanol. You know I ALWAYS recommend dietary changes first. Unfortunately, the average American looks for a quick fix. Seanol is not the whole answer, since it is not a whole diet. But it may dramatically help slow or reverse the damage inflicted by a lifetime of dietary and lifestyle mismanagement.
And, finally, thereís growing evidence that Seanol can treat arthritis, allergies, asthma, and even cancer. At this point, the research is all on animals, so itís very preliminary. But Dr. Haengwoo Lee, who conducted the research, is convinced Seanol will have the same effects on humans.
How can Seanol possibly work on all these illnesses? They all have one thing in common ó inflammation. Here are a few things Dr. Lee found in his Seanol studies:
* ē Seanolís ability to treat arthritis is comparable to Celebrex, the prescription drug that reduces inflammatory cox enzymes. These enzymes can get out of control due to bad diet, stress, injury, infection, and toxins. Seanol significantly reduced pain in a group of knee arthritis patients. But unlike Celebrex, Seanol doesnít cause heart attacks. Instead, it protects your heart.
* ē Seanol reduces inflammatory enzymes, which means it can help improve your allergies. Dr. Lee and his team found that Seanol significantly reduces allergic inflammation in mice. Specifically, Seanol reduced the migration of allergy cells (eosinophils) to the lungs by 75%. Inflammatory white blood cells were reduced by 50%. And mucus plugs in the airways were reduced by 50%.
These findings suggest that Seanol can free your lungs of gunk and acute inflammation. And collagen-causing fibrosis in lung tissue and smooth muscle cell thickness was reduced by 20% and 32% respectively. These latter findings suggest that Seanol compounds can prevent or reverse the progression of chronic lung disease (such as asthma and COPD).
* ē Millions of Americans are afflicted with solar induced basal cell skin cancers. Dr. Lee conducted a study on the effects of Seanol compounds on mice exposed to UV rays. The results were remarkable. Tumor cell division was reduced by 50%. Inflammatory chemicals were reduced by 50-80%. Thatís huge! Weíll need more studies to determine Seanolís ability to treat cancer, but this is very encouraging.
I believe Seanol could be the biggest nutritional discovery weíve seen in a generation. If you have any health condition ó or just want to stay healthy ó Seanol is for you.
I have asked my friends at Advanced Bionutritionals to offer FibroBoost, my favorite Seanol, at an exclusive discount for you. Please follow this link to order or call 800-728-2288 from 8 am to 6:45 pm eastern.