Nattokinase VRS Coumadin Which is More Effective 

According to legend, the warrior Minamoto no Yoshiie found boiled soybeans that had been left on straw and had fermented, leading to the discovery of Natto. By the end of the Edo period (1603-1867), Natto had become a regular part of Japanese culture in some areas. Some believe that Natto (and, by extension, Nattokinase) may play a role in the 50% lower overall incidence of cardiovascular disease in Japan.

Reasons To Use Nattokinase

Nattokinase Benefits & Information

Nattokinase is an enzyme that is extracted from the fermented soy food called "natto." Natto is regarded by the Japanese as a very healthy food and has been consumed there for centuries. Nattokinase, however, has only recently been discovered, isolated and investigated. The research and anecdotal reports are extremely promising, suggesting that including nattokinase in your wellness regime confers several important cardiovascular health benefits such as minimizing the chances of developing heart and vascular diseases.

Nattokinase is valued in the alternative medicine community as a clot-buster and blood thinner, and is sometimes recommended as a substitute for daily aspirin therapy. But its effects go beyond that in terms of catalyzing other enzyme activity.

Nattokinase dissolves fibrin (the tiny fibers) that forms the strong mesh in blood clots. After a heart attack or stroke, the drugs (streptokinase and urokinase) administered intravenously work the same way as Nattokinase. The significant difference is that Nattokinase is natural, non toxic and absorbable by mouth and also believed to be longer-acting. Nattokinase is said to have similar clot-dissolving abilities as plasmin, a biological enzyme in blood.

Alternatively, aspirin reduces stickiness of blood cells (platelets) that, together with fibrin strands, make up blood clots. The drug Coumadin (warfarin) works on abnormal clotting by preventing fibrin strands from forming a clot.

Nattokinase is maximum strength and uses a healthy vegetarian encapsulation and it stands apart by using only 100% Genuine Nattokinase from Japan, Nattokinase was discovered in the 1980s by Dr. Hiroyuki Sumi while researching in Chicago, Illinois, who actually named the enzyme "nattokinase".

Before going off Coumadin and on Nattokinase do these things

1 take copies of my Summary   and this Nattokinase VRS Coumadin Which is More Effective article to your doctor and get his approval.

Order and start taking what is listed in the  Summary  before going off your prescription medicines.

Take the time and effort to read and watch the many health video's I have posted 


Coumadin IV Side Effects

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back, side, muscle, joint, or stomach pain; black, tarry, or bloody stools; blood in the urine (pink or brown urine); bloody or coffee ground-like vomit; chest pain; decreased urination; dizziness; fainting; fever; numbness or tingling; pain, unusual color, or temperature change in any area of the body; pale skin; purple, dark, or painful toes; shortness of breath; skin sores or ulcers; stroke symptoms (eg, confusion, slurred speech, vision problems, one-sided weakness); sudden severe pain in your legs, feet, or toes; trouble swallowing; unexplained swelling; unusual bruising or bleeding (eg, nosebleed, unusual bleeding from gums, increased bleeding from cuts, increased menstrual or vaginal bleeding, coughing up blood, bleeding at the injection site); unusual headache or weakness; unusual pain, swelling, or discomfort; wounds or sores that do not heal properly; yellowing of the skin or eyes.

Coumadin Tablets Side Effects


Coumadin Side Effects - for the Professional

Potential adverse reactions to Coumadin may include:

Rare events of tracheal or tracheobronchial calcification have been reported in association with long-term warfarin therapy. The clinical significance of this event is unknown.

Priapism has been associated with anticoagulant administration; however, a causal relationship has not been established.

Side Effects by Body System


Hematologic side effects including occult and overt bleeding or hemorrhage at any site have been reported the most frequently. Bleeding complications may present as paralysis, paresthesia, headache, chest, abdominal, joint, muscle or other pain, dizziness, shortness of breath, difficulty breathing or swallowing, unexplained swelling, weakness, hypotension, or unexplained shock. Bleeding may result in hematomas, melena, hematuria, ecchymoses, epistaxis, and hematemesis. Spontaneous intraspinal hematomas, spinal cord hemorrhage, gastrointestinal hemorrhage, intracranial hemorrhage, ocular hemorrhage, intra-abdominal hemorrhage, hemopericardium, compartment syndrome following blunt trauma, and other serious bleeding events have been reported. Anemia has been reported infrequently.

Warfarin-induced (Coumadin) intracranial hemorrhage is associated with a high rate of mortality and disability compared with extracranial hemorrhages.

Hematologic risk factors have included history of stroke, a serious comorbid condition, a history of gastrointestinal bleeding, atrial fibrillation, advanced age, and concomitant use of aspirin. In addition, patients with genetic variations in the CYP450 2C9 and VKORC1 enzymes are at a higher risk of bleeding than those without the variation.

A meta-analysis of five randomized controlled trials compared the efficacy and safety of combined oral anticoagulation and antiplatelet therapy versus oral anticoagulants alone after prosthetic heart valve replacement and found an increased risk of general hemorrhage (65%) and gastrointestinal hemorrhage (250%). Embolism and stroke were significantly decreased. The authors conclude that the benefits of decreased risk of thromboembolic events outweigh the toxic effects of combined anticoagulation and antiplatelet therapy.

The results of large observational cohort study (n=13,559) indicate that in patients with nonvalvular atrial fibrillation, the risk of major hemorrhage increases with age, particularly intracranial hemorrhage, whether or not they are receiving warfarin. In patients aged 80 and older the risk of intracranial hemorrhage increases sharply. Also, this study found that among anticoagulated patients with atrial fibrillation, intracranial hemorrhages were responsible for nearly 90% of the deaths from warfarin-associated hemorrhage and the majority of disability among survivors.


Dermatologic side effects including necrosis of the skin and other tissues have been reported in 0.1% to 1.0% of patients. Dermatitis, urticaria, alopecia, rash, bullous eruptions, pruritus, and pallor have been reported infrequently.

Warfarin-induced skin necrosis predominantly affects obese women (4-fold greater occurrence in women) and typically occurs within 10 days of the initiation of therapy, but has occurred after several months or several years of therapy. The majority of lesions (80%) occur in areas with abundant adipose such as the thighs, breasts, abdomen, buttocks, and the extremities. The lesions are usually painful, abrupt in onset, erythematous, purpuric, and sharply demarcated. The proposed mechanism of warfarin-induced skin necrosis involves an imbalance between protein C or protein S and vitamin K-dependent clotting factors. The lesions may resolve spontaneously or progress to form hemorrhagic bullae with subsequent necrosis. Generally, warfarin is withheld; however, discontinuation does not affect lesion progression. Some patients have safely resumed warfarin therapy, but the recommended management in patients who require long-term anticoagulation is resumption of warfarin at a lower dose in conjunction with heparin bridge therapy. The dosage of warfarin should be slowly titrated until a therapeutic INR is reached.

One case of warfarin-induced skin necrosis of the eyelids has been reported. In this case, the patient developed bilateral periorbital ecchymoses with full-thickness necrotic lesions in the medial canthal region.


Other side effects have been reported infrequently. These have included purple toe syndrome.


Cardiovascular side effects have included systemic atheroemboli and cholesterol microemboli, which present with a variety of signs and symptoms. These have included purple toe syndrome, livedo reticularis (blue tingeing of the skin), rash, gangrene, abrupt and intense pain in the leg, foot, or toes, foot ulcers, myalgia, penile gangrene, abdominal pain, flank or back pain, hematuria, renal insufficiency, hypertension, cerebral ischemia, spinal cord infarction, pancreatitis, symptoms simulating polyarteritis, or any other sequelae of vascular compromise due to embolic occlusion. Hemopericardium and cardiac tamponade have also been reported. Hypotension, edema, angina syndrome, and chest pain have been reported infrequently.


Hepatic side effects have been reported infrequently. These have included jaundice, intrahepatic cholestasis, hepatitis, and elevated liver enzymes.


Renal side effects have been reported infrequently. These have included hematuria, acute renal failure due to interstitial nephritis, and renal hematomas.


A meta-analysis of five randomized controlled trials compared the efficacy and safety of combined oral anticoagulation and antiplatelet therapy versus oral anticoagulants alone after prosthetic heart valve replacement and found an increased risk of general hemorrhage (65%) and gastrointestinal hemorrhage (250%). Embolism and stroke were significantly decreased. The authors conclude that the benefits of decreased risk of thromboembolic events outweigh the toxic effects of combined anticoagulation and antiplatelet therapy.

Gastrointestinal side effects have been reported infrequently. Nausea, diarrhea, abdominal cramping, vomiting, and flatulence/bloating have been reported. Gastrointestinal bleed has occurred when warfarin was combined with aspirin for antithrombotic effects after placement of heart valves.


Warfarin-induced priapism has been reported. In one case report, a 16 year old male patient had been treated with warfarin for a deep venous thrombosis in his leg. The patient experienced a hypercoagulable state upon initiation of warfarin therapy because he also had an undocumented protein C deficiency. This led to an increased risk of thromboembolism that manifested as priapism and skin necrosis.

Genitourinary side effects have included priapism.


Hypersensitivity reactions including anaphylactic reactions have been reported infrequently. A case of leukocytoclastic cutaneous vasculitis has been reported.

Nervous system

Nervous system side effects have been reported rarely. These have included fever, fatigue, lethargy, malaise, asthenia, pain, headache, dizziness, taste perversion, cold intolerance, and paresthesia including feeling cold and chills, syncope, loss of consciousness, and coma.


Respiratory side effects have been reported rarely. These have included tracheal or tracheobronchial calcification.


Ocular side effects have included subconjunctival hemorrhage and retinal hemorrhage.


Cesarone MR, Belcaro G, Nicolaides AN, Ricci A, Geroulakos G, Ippolito E, Brandolini R, Vinciguerra G, Dugall M, Griffin M, Ruffini I, Acerbi G, Corsi M, Riordan NH, Stuard S, Bavera P, Di Renzo A, Kenyon J, Errichi BM. Prevention of venous thrombosis in long-haul flights with Flite Tabs: the LONFLIT-FLITE randomized, controlled trial. Angiology. 54.5 (2003) 531-539.

Sumi H, Hamada H, Nakanishi K, Hiratani H. Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol. 84.3 (1990): 139-143.

Dare to question!!!! Take what the body needs to Live healthy and  without pain.

I talked to a 66 year old man who has not went to a doctor in 8  years ;who is taking most of what you see here.  He appears to be in excellent health.


If more people gave their bodies the vitamins and minerals in the amounts needed there would be far fewer heart stints & bypasses, fewer knee replacements, fewer cancers & chemo therapies, pneumonia, colds, flue & fewer other health problems. The lack of sickness would be very bad news for hospitals, doctors, nurses, dentists, insurance companies, drug companies, drug stores &  physical therapists.


I am 76 and have no known major health problems or pain. Based on what I know now I will never take a Statin Drug, Wolfram, Fozamax, Fortical , Plavix, blood pressure medicines, High Fructose Corn Syrup, brush my teeth with  Fluoride tooth paste or an Aspirin, or  drink milk, as I find they are harmful to  health. There are much better vitamins, mineral and food supplement solutions. 

To be healthy Eat far more vegetables, fruits and far less meat.


My 81 year old wife who had 3 strokes, a heart attack and triple bypass, has borderline sugar diabetics and high blood pressure. She is now off all prescription medicines. She has less problems and appears to be doing much better.


Questions ? Does your doctor go along with what you are doing?

Answer. Yes for me. But he said go off the blood pressure medicines by taking 1/2 half as much for a week.  He took me off the prostrate medicines and now I have a powerful stream. As for my wife Gloria I haven't talked with the doctor yet; but I will.


 Question ? Don't you  accept what your doctor says you should take?

Answer? Yes if the doctor advice agrees with  many different Doctors at major  health  research collages. I check out everything from many different Doctors at major  health  research collages.  I find most doctors, including mine, have little knowledge on the effects of evidence based  vitamins, mineral and food supplement solutions.