S.K. DEY, Ph.D
dorthy overall wells
professor of pediatrics, department of pediatrics, departments of cell and developmental biology and pharmacology
Deys laboratory has been engaged for more than three decades in defining the molecular and genetic basis of preimplantation embryo development and embryo-uterine interactions during blastocyst implantation. His group has addressed critical roles of growth factors, regulatory molecules, cytokines, and lipid mediators in the uterus and embryo during early pregnancy. The work from Deys laboratory has been published in numerous peer-reviewed journals including Nature, Science, Cell, PNAS, Genes & Development, Development, Developmental Biology, JBC and Molecular Endocrinology. His ongoing research is to elucidate critical role of ligand-receptor signaling with endocannabinoids, roles cPLA2-COX-2 derived prostaglandins, PPARs, LIF, Hoxa-10 and roles of developmental genes in implantation and pregnancy establishment. His group is also engaged in studying global gene and protein expression profiles in the uterus and embryo during implantation by employing genomics and proteomics approaches.