The Division of Reproductive and Developmental Biology Department of Pediatrics at Vanderbilt University Medical Center VU Help Search Vanderbilt Medical Center Jeff Reese, MD Sanjoy K. Das, Ph.D Bibhash C. Paria, Ph.D S. K. Dey, Ph.D
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VASCULAR PERMEABILITY AND ANGIOGENESIS
Increased vascular permeability and angiogenesis are hallmarks for successful implantation. Multiple elements that effect vessel formation and vascular integrity are implicated in the establishment of pregnancy. The following papers demonstrate our recent work in this area.

Ma W, Tan J, Matsumoto H, Robert B, Abrahamson DR, Das SK, Dey SK.
Adult tissue angiogenesis: evidence for negative regulation by estrogen in the uterus.
Mol Endocrinol. 2001 Nov;15(11):1983-92.


Zhao X, Ma W, Das SK, Dey SK, Paria BC.
Blastocyst H(2) receptor is the target for uterine histamine in implantation in the mouse.
Development. 2000 Jun;127(12):2643-51.


Halder JB, Zhao X, Soker S, Paria BC, Klagsbrun M, Das SK, Dey SK.
Differential expression of VEGF isoforms and VEGF(164)-specific receptor neuropilin-1 in the mouse uterus suggests a role for VEGF(164) in vascular permeability and angiogenesis during implantation.
Genesis. 2000 Mar;26(3):213-24.


Dey, S.K. and D.C. Johnson.
Reevaluation of histamine in implantation.
The Endometrium. (F. Kimball, ed.) Spectrum Publication, New York, pp. 269-283, 1980.


Paria BC, Zhao X, Das SK, Dey SK and Yoshinaga Y.
Zonula occludens-1 (ZO-1) and E-cadherin are coordinately expressed in the mouse uterus with initiation of implantation and decidualization.
Dev Biol 208:488-501, 1999.


Paria BC, Das N, Das SK, Zhao X, Dileepan KN and Dey SK.
Histidine decarboxylase gene in the mouse uterus is regulated by progesterone and correlates with uterine differentiation for blastocyst implantation.
Endocrinology 139:3958-3966, 1998.
 

Chakraborty I, Das SK and Dey SK. Differential expression of vascular endothelial growth factor and its receptor mRNAs in the mouse uterus during the periimplantation period.
J Endocrinol 147:339-352, 1995.
 

Hudgins, L. and S.K. Dey.
Preimplantation embryo development in the mouse: Role of histidine decarboxylase. Gamete Res. 6:121, 1982.
 

Dey, S.K. and C.J. Hubbard.
Role of histamine and cyclic nucleotides in implantation in the rabbit.
Cell Tissue Research 220:549, 1981.
 

Cox, C.L., S. Mukerjee, M. Jackson and S.K. Dey.
Effect of inhibition of histidine decarboxylase on implantation in the mouse. Contraception 23:457, 1981.
 

Dey, S.K.
Role of histamine in implantation: inhibition of histidine decarboxylase induces delayed implantation in the rabbit.
Biol. Reprod. 24:867, 1981
 

Dey, S.K. and D.C. Johnson.
Histamine formation by mouse preimplantation embryos.
J. Reprod. Fert. 60:457, 1980.
 

Johnson, D.C. and S.K. Dey.
Role of histamine in implantation. Dexamethasone inhibits estradiol-induced implantation in the rat.
Biol. Reprod. 22:1135, 1980
 

Dey, S.K., D.C. Johnson and J.G. Santos.
Is histamine production by the blastocyst required for implantation in the rabbit?
Biol. Reprod. 21:1169, 1979.
 

Dey, S.K., C. Villanueva and N.I, Abdou.
Histamine receptors on rabbit blastocyst and endometrial cell membranes.
Nature 278:648, 1979.
 

Dey, S.K., C. Villanueva, S.M. Chien and R.D. Crist.
Role of histamine in implantation in the rabbit.
J. Reprod. Fert. 53:23, 1978.

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