The Division of Reproductive and Developmental Biology Department of Pediatrics at Vanderbilt University Medical Center VU Help Search Vanderbilt Medical Center Jeff Reese, MD Sanjoy K. Das, Ph.D Bibhash C. Paria, Ph.D S. K. Dey, Ph.D
The Division of Reproductive and Developmental Biology



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EMERGING CONCEPTS
Research in our laboratories has led to novel insights in other fields of biology and medicine. The following papers reflect some of our recent publications and collaborative work in areas outside the reproductive tract.

Mammary Gland Development

Brisken C, Ayyannan A, Nguyen C, Heineman A, Reinhardt F, Tan J, Dey SK, Dotto GP, Weinberg RA, Jan T. IGF-2 is a mediator of prolactin-induced morphogenesis in the breast.
Dev Cell. 2002 Dec;3(6):877-87.

Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA.
Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling.
Genes Dev. 2000 Mar 15;14(6):650-4.


Cancer Biology

Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN.
Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor
production in ovarian cancer.
Cancer Res. 2003 Mar 1;63(5):906-11.

Jaeckel EC, Raja S, Tan J, Das SK, Dey SK, Girod DA, Tsue TT, Sanford TR.
Correlation of expression of cyclooxygenase-2, vascular endothelial growth factor, and peroxisome proliferator-activated receptor delta with head and neck squamous cell carcinoma.
Arch Otolaryngol Head Neck Surg. 2001 Oct;127(10):1253-9.

Tong BJ, Tan J, Tajeda L, Das SK, Chapman JA, DuBois RN, Dey SK.
Heightened expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-delta in human endometrial adenocarcinoma.
Neoplasia. 2000 Nov-Dec;2(6):483-90.

Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN.
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer.
Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13275-80.

Williams CS, Tsujii M, Reese J, Dey SK, DuBois RN.
Host cyclooxygenase-2 modulates carcinoma growth.
J Clin Invest. 2000 Jun;105(11):1589-94.


Other Areas

Hough LB, Nalwalk JW, Stadel R, Timmerman H, Leurs R, Paria BC, Wang X, Dey SK.
Related Articles, Links Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors.
J Pharmacol Exp Ther. 2002 Oct;303(1):314-22.

Casado M, Callejas NA, Rodrigo J, Zhao X, Dey SK, Bosca L, Martin-Sanz P.
Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy.
FASEB J. 2001 Sep;15(11):2016-8.

Deutsch DG, Goligorsky MS, Schmid PC, Krebsbach RJ, Schmid HH, Das SK, Dey SK, Arreaza G, Thorup C, Stefano G, Moore LC.
Production and physiological actions of anandamide in the vasculature of the rat kidney.
J Clin Invest. 1997 Sep 15;100(6):1538-46.

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