The Division of Reproductive and Developmental Biology Department of Pediatrics at Vanderbilt University Medical Center VU Help Search Vanderbilt Medical Center Jeff Reese, MD Sanjoy K. Das, Ph.D Bibhash C. Paria, Ph.D S. K. Dey, Ph.D
The Division of Reproductive and Developmental Biology



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STEROID HORMONES AND ENVIRONMENTAL MIMICS
All aspects of reproduction are influenced by the ovarian steroid hormones estrogen and progesterone. The mechanisms of their action via classical estrogen and progesterone receptors and through other signaling pathways are an active area of interest in our laboratories. The following papers highlight our recent contributions to the understanding of steroid hormone actions in embryo-uterine signaling.

Ma WG, Song H, Das SK, Paria BC, Dey SK.
Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2963-8.


Matsumoto H, Zhao X, Das SK, Hogan BL, Dey SK.
Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus.
Dev Biol. 2002 May 15;245(2):280-90.


Das SK, Tan J, Raja S, Halder J, Paria BC, Dey SK.
Estrogen targets genes involved in protein processing, calcium homeostasis, and Wnt signaling in the mouse uterus independent of estrogen receptor-alpha and -beta.
J Biol Chem. 2000 Sep 15;275(37):28834-42.


Tan J, Paria BC, Dey SK, Das SK.
Differential uterine expression of estrogen and progesterone receptors correlates with uterine preparation for implantation and decidualization in the mouse.
Endocrinology. 1999 Nov;140(11):5310-21.


Lim H, Ma L, Ma WG, Maas RL, Dey SK.
Hoxa-10 regulates uterine stromal cell responsiveness to progesterone during implantation and decidualization in the mouse.
Mol Endocrinol. 1999 Jun;13(6):1005-17.


Paria BC, Tan J, Lubahn DB, Dey SK, Das SK.
Uterine decidual response occurs in estrogen receptor-alpha-deficient mice.
Endocrinology. 1999 Jun;140(6):2704-10.


Paria BC, Tan J, Lubahn DB, Dey SK and Das SK.
Uterine decidual response occurs in estrogen receptor-a deficient mice.
Endocrinology 140:2704-2710, 1999.
 

Das SK, Taylor JA, Korach KS, Paria BC, Dey SK and Lubahn.
Estrogenic responses in estrogen receptor-alpha deficient mice reveal a distinct estrogen signaling pathway.
Proc Natl Acad Sci USA 94:12786-12791, 1997.
 

Hou Q, Paria BC, Mui C, Dey SK and Gorski J.
Immunolocalization of estrogen receptor protein in the mouse blastocyst during normal and delayed implantation.
Proc Natl Acad Sci USA 93:2376-2381, 1996. 

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