The Division of Reproductive and Developmental Biology Department of Pediatrics at Vanderbilt University Medical Center VU Help Search Vanderbilt Medical Center Jeff Reese, MD Sanjoy K. Das, Ph.D Bibhash C. Paria, Ph.D S. K. Dey, Ph.D
The Division of Reproductive and Developmental Biology



Home
What's New
Research Areas
Investigators
LinksContact Us


Understanding the complex interactions between the embryo and uterus during pregnancy is essential for alleviating the problems of infertility, ensuring the birth of healthy offspring, and developing improved contraceptives. The following publications highlight what's new in our labs and reflect our most recent effots to elucidate the molecular mechanisms of reproduction.

CLICK HERE TO VIEW OUR COVER ARTICLES

Wang X, Wang H, Matsumoto H, Roy SK, Das SK, Paria BC
Dual source and target of heparin-binding EGF-like growth factor during the onset of implantation in the hamster.
Development. 2002 Sep;129(17):4125-34.


Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN.
Cyclooxygenase-1 is Overexpressed and Promotes Angiogenic Growth Factor Production in Ovarian Cancer.
Cancer Res. 2003 Mar 1;63(5):906-911.


Ma WG, Song H, Das SK, Paria BC, Dey SK.
Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2963-8.


Brisken C, Ayyannan A, Nguyen C, Heineman A, Reinhardt F, Tan J, Dey SK, Dotto GP, Weinberg RA.
IGF-2 Is a Mediator of Prolactin-Induced Morphogenesis in the Breast.
Dev Cell. 2003 Feb;4(2):283.


Paria BC, Wang H, Dey SK.
Endocannabinoid signaling in synchronizing embryo development and uterine receptivity for implantation.
Chem Phys Lipids. 2002 Dec;121(1-2):201-10.


Daikoku T, Matsumoto H, Gupta RA, Das SK, Gassmann M, DuBois RN, Dey SK.
Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy.
J Biol Chem. 2003 Feb 28;278(9):7683-91.


Brisken C, Ayyannan A, Nguyen C, Heineman A, Reinhardt F, Tan J, Dey SK, Dotto GP, Weinberg RA, Jan T.
IGF-2 is a mediator of prolactin-induced morphogenesis in the breast.
Dev Cell. 2002 Dec;3(6):877-87.


Leach RE, Romero R, Kim YM, Chaiworapongsa T, Kilburn B, Das SK, Dey SK, Johnson A, Qureshi F, Jacques S, Armant DR.
Pre-eclampsia and expression of heparin-binding EGF-like growth factor.
Lancet. 2002 Oct 19;360(9341):1215-9.


Hough LB, Nalwalk JW, Stadel R, Timmerman H, Leurs R, Paria BC, Wang X, Dey SK.
Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors.
J Pharmacol Exp Ther. 2002 Oct;303(1):314-22.


Lim H, Dey SK.
A novel pathway of prostacyclin signaling-hanging out with nuclear receptors.
Endocrinology. 2002 Sep;143(9):3207-10. 12:


Paria BC, Reese J, Das SK, Dey SK.
Deciphering the cross-talk of implantation: advances and challenges.
Science. 2002 Jun 21;296(5576):2185-8.


Song H, Lim H, Paria BC, Matsumoto H, Swift LL, Morrow J, Bonventre JV, Dey SK.
Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development.
Development. 2002 Jun;129(12):2879-89.


Matsumoto H, Ma WG, Daikoku T, Zhao X, Paria BC, Das SK, Trzaskos JM, Dey SK.
Cyclooxygenase-2 differentially directs uterine angiogenesis during implantation in mice.
J Biol Chem. 2002 Aug 9;277(32):29260-7. 15:


Matsumoto H, Zhao X, Das SK, Hogan BL, Dey SK.
Indian hedgehog as a progesterone-responsive factor mediating epithelial-mesenchymal interactions in the mouse uterus.
Dev Biol. 2002 May 15;245(2):280-90.

Vanderbilt University is committed to principles of equal opportunity and affirmative action.
Copyright © 2003, Vanderbilt Medical Center, 21st Avenue South and Garland Avenue
Last modified: June 1, 2003

"Links contained on this page to information provided by other organizations are presented as a service and neither constitutes nor implies Vanderbilt University Medical Center endorsement or warranty."